Efficacy tests of Rifamycin
2004
Spakauskas, V.(Lithuanian Veterinary Academy, Kaisiadorys (Lithuania)) | Klimiene, I.(Lithuanian Veterinary Academy, Kaisiadorys (Lithuania)) | Bandzaite, V.(Lithuanian Veterinary Academy, Kaisiadorys (Lithuania))
Preparation Rifamycin for treatment of mastitis in cows during lactation was tested for efficacy at the Lithuanian Veterinary Academy Veterinary Institute and individual Farm of Kaisiadorys district in 2002-2003. The antimicrobial activity of the preparation in vitro was examined using the method of agar-diffusion. Milk samples were investigated bacteriological using Mastest and a device Anadis for counting of somatic cells. The elimination of antibiotic with milk was examined before the administration of the preparation and 12, 24, 48, 60, 72 and 84 hours after the administration. The efficacy of the preparation was evaluated by comparison of the incidence of mastitis and duration of disease as well as the number of cows who recovered in control and experimental groups. Rifamycin in vitro is most efficient against Staphylococci (sensitivity zone - 24.4 +- 2.0 mm) and rather efficient against Streptococci (17.2 +- 2.5 mm). The effect on Escherichia and Fungus in vitro was weak. The total of 10 treated cows with mastitis recovered. This was determined by clinical trials and laboratory tests of milk samples. After the administration of Rifamycin inhibitory substances in milk were identified after 12, 24, 36, 48 and 60 hours. 72 hours after the administration no inhibitory substances in milk were found.
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