Therapeutic drug trial in albino mice against trypanosomiasis
2005
Ahmad, S. | Nasir, A.A. | Awan, A.H.,Veterinary Research Inst.,Lahore (Pakistan)
This study was conducted to determine the trypanocidal efficacyof Antrycide, Fatrybanil and Trypamedium in albino miceexperimentally infected subcutaneously with Trypanosoma evansi. Forthis purpose, 25 albino mice were randomly divided into five equalgroups i.e. A, B, C, D and E. Groups A, B and C were infected andthen treated with Antrycide, Fatrybanil and Trypamedium,respectively. Group D was kept as infected and group E non-infectedcontrol. On the basis of blood smear examination, the efficacy ofAntrycide and Fatrybanil was found 100% when used in single doseas compared to Trypamedium which was 100% effective with seconddose.
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