Inhibitory effects of D-psicose on glycemic responses after oral carbohydrate tolerance test in rats
2006
Matsuo, T.(Kagawa Univ., Miki (Japan). Faculty of Agriculture)
D-Psicose is one of the rare sugars present in small quantities in commercial carbohydrates and agricultural products. We studied the effects of D-psicose and psico-rare sugar (a mixture of 75% D-fructose and 25% D-psicose) on glycemic responses after oral carbohydrate tolerance tests in rats. Male Wistar rats (6 months old) were administrated 2 g/kg sucrose, maltose or soluble starch together with 0.2 g/kg D-psicose or psico-rare sugar. D-Psicose or psico-rare sugar significantly inhibited the increment of plasma glucose concentration induced by sucrose or maltose. The starch-induced glycemic response tended to be suppressed by D-psicose or psico-rare sugar, although not to a significant degree. These results suggest that D-psicose and psico-rare sugar are functional monosaccharides that suppress the glycemic response after carbohydrate ingestion.
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