Effect of β-carotene Supplementation on Lipid Peroxides and Antioxidative Enzyme Activities in Hyperlipidetmic Rats
2004
Song, Y.O. (Inha University, Inchon, Republic of Korea) | Chyun, J.H. (Inha University, Inchon, Republic of Korea)
This study was performed to investigate the effect of dietary β-carotene supplementation on lipid metabolism and antioxidant enzyme activities in hyperlipidemic rats. Fifty Sprague-Dawley male rats aging 7 weeks were fed the control diet (CD, 5% corn oil) and the high fat diet (HFD, 15% beef tallow + 1% cholesterol) for 4 weeks and then 0.02% β-carotene was supplemented to CD and HFD group for 8 more weeks. Serum lipid compositions, lipid peroxides and antioxidative enzymes in liver were analyzed at 4, 8 and 12week of the experiment.
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