Detection of Novel Mutations in the FABP3 Promoter Region and Association Analysis with Intramuscular Fat Content in Pigs
2005
Kim, J.H. (Gyeongsang National University, Jinju, Republic of Korea) | Park, E.W.; Choi, B.W.; Kim, T.H.; Cheong, I.C.; Oh, S.J. (National Livestock Research Institute, RDA, Suwon, Republic of Korea) | Park, J.J. (Gyeongsang National University, Jinju, Republic of Korea) | Seo, B.Y. (Gyeongsang National University, Jinju, Republic of Korea) | Lim, H.T. (Gyeongsang National University, Jinju, Republic of Korea) | Lee, J.G. (Gyeongsang National University, Jinju, Republic of Korea) | Jeon, J.T. (Gyeongsang National University, Jinju, Republic of Korea), E-mail: [email protected] | Choi, B.W. (National Livestock Research Institute, RDA, Suwon, Republic of Korea) | Kim, T.H. (National Livestock Research Institute, RDA, Suwon, Republic of Korea) | Cheong, I.C. (National Livestock Research Institute, RDA, Suwon, Republic of Korea) | Oh, S.J. (National Livestock Research Institute, RDA, Suwon, Republic of Korea)
Intramuscular fat content(IMF) is considered as one of major economic traits in the pig breeding and industry. In general, high IMF results in better meat quality. Several approaches to detect quantitative trait loci(QTL) for IMF indicated a strong possibility of the existence of a QTL related to IMF between the microsatellite marker SW71 and SW1881 on SSC6q. Porcine FABP3 has been considered as a candidate gene affecting IMF due to its physiological roles and position on the pig genome. Two novel mutations, g.-114TC and g.-158TG were detected by duplicate sequencing of the porcine FABP3 promoter region.
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