The Hypocholesterolemic Effect of Green Tea EGCG Was Not Mediated Via the Stimulation of the Low-Density Lipoprotein Receptor Gene Expression in Cholesterol-Fed Rats
2005
Moon, H.J. (Ewha Womans University, Seoul, Republic of Korea) | Kim, Y.H. (Ewha Womans University, Seoul, Republic of Korea), E-mail: [email protected]
Green tea, which has high polyphenols amount, is thought to have hypocholesterolemic effects. The present study was performed to further examine the hypocholesterolemic action of green tea, especially (-) epigallocatechin gallate (EGCG) for its effect on diet-induced hypercholesterolemia in rats. Male Sprague-Dawley rats (n=15) were fed a green tea-free diet (control), 1.0% green tea catechin (catechin) or 0.5% green tea catechin EGCG for seven weeks. Hypercholesterolemia was induced by adding 1% cholesterol and 0.5% cholic acid to all diets.
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