Restriction of protein intake improved blood component levels in a bovine with Claudin-16 deficiency
2007
Annaka, A.(Kitasato Univ., Towada, Aomori (Japan). School of Veterinary Medicine and Animal Sciences) | Ikeda, H. | Iizuka, Y. | Naganawa, N. | Ando, T. | Park, C.H. | Ohtsuka, H. | Hoshi, F. | Oyamada, T. | Watanabe, D.
A 9-month-old Japanese black bovine with Claudin-16 (CL-16) deficiency was maintained on a low-protein diet to reduce the load on the kidneys. At the time of the first examination, the animal had slight anemia and lameness, and high plasma levels of urea nitrogen (UN), creatinine (Crea), total cholesterol (T-chol) and vitamin A (VA). After 40 days on the low protein diet, the clinical symptoms improved, and the values of plasma biochemical variables decreased. But Crea and VA levels remained high, although showing some decrease. These results suggest that a low protein diet might improve blood component levels in cattle with CL-16 deficiency.
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