Canine ovarian serous papillary adenocarcinoma with neoplastic hypercalcemia
2006
Hori, Y.(Kitasato Univ., Towada, Aomori (Japan). School of Veterinary Medicine and Animal Sciences) | Uechi, M. | Kanakubo, K. | Sano, T. | Oyamada, T.
A female golden retriever was referred to assess a history of a palpable abdominal mass. A serum chemistry analysis revealed elevated concentrations of blood urea nitrogen, creatinine, calcium, and parathyroid hormone-related protein (PTH-rP). Exploratory laparotomy revealed an ovoid mass within the right ovary. This mass was removed surgically by performing an ovariohysterectomy. The right ovarian mass was diagnosed as a serous papillary adenocarcinoma. Following surgery, the dog recovered, and the serum calcium and PTH-rP concentrations decreased. Therefore, concentrations of PTH-rP and calcium might be associated with serous papillary adenocarcinomas. Serial evaluation of the serum PTH-rP and calcium was useful for evaluating the prognosis.
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