The role of progesterone IGF-I and IGFB-3 in regulation of porcine sexual maturation
2005
Kolesarova A.(Slovenska polnohospodarska univ. v Nitre (Slovak Republic). Katedra fyziologie zivocichov, Tr. A. Hlinku 2, 949 76 Nitra | Sirotkin A.Vyskumny ustav zivocisnej vyroby, Nitra (Slovak Republic). Hlohovska 2, 949 01 Nitra | Kramarova M.Slovenska polnohospodarska univ. v Nitre (Slovak Republic) | Massanyi, P.
The aim of our experiments was to study the influence of level of progesterone (P4), insulin-like growth factor I (IGF-I), IGF-binding protein-3 (IGFBP-3) in blood plasma and the release of these substances by porcine ovarian granulosa cells cultured in vitro on sexual maturation. Gilts were divided in two groups according to the sexual maturation (sexually immature gilts and sexually mature gilts). By radioimmunoassay and immunocytochemistry we determined, that sexual maturation of gilts is associated with an increase content of P4, IGF-I, IGFBP-3 in blood plasma and granulosa cells. These data demonstrate the ability of P4, IGF-I and IGFBP-3 to regulation of porcine sexual maturation.
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