The effect of caffeine on selected metabolic parameters and the health of cattle
Link, R.(University of Veterinary Medicine, Kosice (Slovak Republic) | Kovac, G. | Nagy, O.
The aim of the trial was to determine haematological parameters, some enzymes and state of health after intra- venous application of caffeine to six cows. Caffeine, at a dose 4.2 g, was administered to cows in vena jugularis. Their state of health was checked by clinical examination and blood was sampled before application and one, three,six and twenty-four hours after application. The temperature of the animals was within a normal physiological range during the whole period of the experiment. We observed a slight increase in temperature in the first hour. Heart rate decreased mildly over six hours, but twenty-four hours after administration it was same as at the beginning of the experiment. The intravenous application significantly influenced the haematological parameters in the first hour. The number of erythrocytes decreased from 6.5 T/l to 5.8 T/l,which was statistically significant (p < 0.05), packed cell volume also decreased from 0.28 l/l to 0.23 l/l (p < 0.01). Three hours after application the number of erythrocytes increased to 6.11 T/l and the significant difference disappeared. The number of leukocytes and haemoglobin concentration was constant during the experiment. The activity of AST was not influenced by preparation.The activity of CPK was also in a normal physiological range,but at the 24th hour we found a significant decrease.
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