Diagnoses of canine and feline malignant lymphomas using the new WHO classification
2008
Sakai, Y.(Tokyo Univ. (Japan)) | Uetsuka, K. | Nakayama, H.
Fifty seven canine and 26 feline cases of malignant lymphoma were reviewed histopathologically and by immunohistochemistry and flow-cytometry using T- and B-cell markers. Based on these results, each case was diagnosed according to the WHO 2nd classification of malignant lymphoma of domestic animals. Anatomical classification was also conducted. In both animals, B-cell lymphomas were predominant in up to two-thirds of all cases. In particular, large B-cell lymphoma accounted for one-third of the cases. Of T/NK cell lymphomas, large granular lymphoproliferative disorders were most common in both dogs and cats. More than half of canine lymphomas were multicentric forms, while feline lymphomas were observed in various organs.
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