INFLUENCE OF THE MULTIENZYMATIC PREPARATIONS HOSTAZYM C 100 AND HOSTAZYM X 100 ON SOME BIOCHEMICAL PARAMETERS IN THE BLOOD OF YEARLING RAMS | Ефект на мултиензимните препарати НOSTAZYM C 100 и HOSTAZYM X 100 върху някои показатели в кръвта на шилета

The purpose of this study was to test the effect of the multienzymatic preparations Hostazym C 100 and Hostazym X 100 on same biochemical parameters in the blood of yearling rams that have a significant clinical relevance. An experiment was conducted with nine male yearling rams from the Blackhead Pleven breed with an average live weigh of 45.200 kg at the beginning of the study. They were divided into three groups of three animals each and were housed in individual stalls. The study was organized into three periods – a control and two experimental ones. During the control period the first group yearling rams were fed ration consisting of 1 kg of barley and 1 kg of hay meadows, the second group - 0.800 kg of barley, 0.200 kg of sunflower meal and 1 kg of hay meadow, and the third group - with a diet consisting of 0.800kg of barley, 0.200 kg of sunflower expeller and 1 kg of meadow hay. During the first experimental period the rations of the three groups of animals were supplemented with the enzyme preparation Hostazym C 100 at a dose of 1g/kg concentrated feed, mixed with the concentrate 10 days before feeding. In the second experimental period the concentrated feed in the three groups tested was supplemented with the enzyme preparation Hostazym X 100 at the same dose and route of administration. The enzymatic preparations decreased the total cholesterol content in the blood before eating the ration consisting of 1 kg of barley and 1kg of hay meadows and in the ration containing 0.800 kg of barley, 0.200 kg of sunflower meal and 1 kg of meadow hay - P 0.05 to 0.01. The multienzymatic product Hostazym C 100 decreased the values of the ratio total cholesterol / HDL-cholesterol, regardless of the lipid and protein level in the ration - P0.05-0.001. Based on the analysis of the concentration of L–aspartate 2–oxoglutarate aminotransferase - ASAT, L-alanine 2-oxoglutarate aminotransferase - ALAT, γ - glutamyltransferase - γ -GT and alkaline phosphatase in the blood serum it was obtained that Hostazym C 100 and Hostazym X 100 did not have a negative effect on the physiological activity of the liver or on the health status of the studied animals.