Effects of D-psicose on body fat accumulation and high fructose corn syrup diets in rats
2010
Yamada, T., Matsutani Chemical Industry Co. Ltd., Itami, Hyogo (Japan) | Iida, T. | Hayashi, N. | Oga, H. | Okuma, K. | Izumori, K.
In this study, we examined the preventing effect of D-psicose on the accumulation of body fat in rats. Four-week-old Wistar rats were fed with a high fructose corn syrup(HFCS) diet or a HFCS diet containing 1.3%, 2.6%, 3.9% or 5.2% of D-psicose for 5 weeks. The effects of D-psicose on body weight, food intake, total fat and various blood biochemical parameters were examined. Rats fed with HFCS diet containing 5.2% of D-psicose showed a significant reduction in body weight compared to those fed with HFCS diet. The groups given D-psicose showed dose-dependent decrease in perirenal fat and total fat weight. These results suggest that D-psicose has an effect to prevent the accumulation of body fat against HFCS intake.
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