Effects of acepromazine maleate on intraocular pressure and pupil diameter in dog's eye
2009
Kovalcuka, L., Latvia Univ. of Agriculture, Jelgava (Latvia) | Birgele, E., Latvia Univ. of Agriculture, Jelgava (Latvia)
The research was performed at the Faculty of Veterinary Medicine of the Latvia University of Agriculture. At the moment the research in veterinary anaesthesia is in its infancy stage. The aim of this study was to determine the effects of the acepromazine maleate on intraocular pressure (IOP) and horizontal pupil diameter (HPD) in a dog's eye. Ten adult dogs of different age, breed and sex were examined clinically and ophthalmologically. All animals were clinically and ophthalmologically healthy. Animals received acepromazine intramuscularly. IOP and HPD were measured every 5 minutes for the total period of 60 minutes. It was established that the acepromazine maleate intramuscular injection causes an IOP decrease in booth eyes. A significant IOP decrease was observed from 35 till 60 minutes after the acepromazine injection. The pupil contraction was observed 5 minutes after the treatment and continued to contract till the end of the research. As acepromazine maleate causes a significant decrease of intraocular pressure, it is not contraindicated to be used in the case of corneal trauma, perforation, glaucoma and corneal ulcers.
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