Characterization of HR region of gp41 of HIV
2010
Qadir, M.I. (Government Coll. Univ., Faisalabad (Pakistan). Coll. of Pharmacy) | Malik, S.A. (Quaid-i-Azam Univ., Islamabad (Pakistan). Dept. of Biochemistry) | Tehzeeb-ul-Nisa (Government Coll. Univ., Faisalabad (Pakistan). Coll. of Pharmacy) | Tabassum, N. (COMSAT Inst. of Information Technology, Abbottabad (Pakistan). Dept. of Chemistry) | Ali, S. (Quaid-i-Azam Univ., Islamabad (Pakistan). Dept. of Microbiology) | Nisar, L. (Quaid-i-Azam Univ., Islamabad (Pakistan). Dept. of Biochemistry)
The present study was conducted to assess HIV infection by reverse transcriptase polymerase chain reaction (RT-PCR) by using primers based on sequence of gp41, which is a more conservative region than the previously used regions. The study was carried out on 200 individuals: 100 normal (HIV seronegative) individuals, and 100 patients who were HIV seropositive. The HR region of gp41 gene of HIV was characterized. So it may be concluded that "characterization of this region with the said primers" may be used for the diagnosis of AIDS.
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