Izmeneniya biologicheskikh i fiziko-khimicheskikh svojstv gemagglyutinina H2 ptich' ego virusa grippa A v protsesse adaptatsii k novomu khozyainu.
1995
Lipatov A.S. | Gitel'man A.K. | Govorkova E.A. | Smirnov Yu.A.
Avian influenza A virus with H2 hemagglutinin has been adapted to mice for the first time. Alterations in the hemagglutinin of adapted variants of the virus as a result of adaptation to a new host are described. Hemagglutinin of a hightly virulent adapted variant differed from the parental avirulent strain by antigenic structure, electrophoretic mobility, and receptor activity during interactions with murine red cells.
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