Pharmacotoxicological characteristics of a complex mineral preparation 'Hexamin' in experiments on laboratory animals | Фармако-токсикологические свойства комплексного минерального препарата 'Гексамин' в опытах на лабораторных животных
2011
Kuchinskij, M.P. | Verigo, Yu.V., National Academy of Sciences. Scientific and Practical Center of Animal Breding (Belarus). The S.N. Vyshelesskij Inst. of Experimental Veterinary Medicine
Study on pharmacodynamics of new complex mineral preparation 'Hexamin' (created by experts of The S.N. Vyshelesskij Inst. of Experimental Veterinary Medicine and Institute of Physical Organic Chemistry of the National Academy of Sciences (Belarus)) on laboratory animals; assessment of toxicological effects and impact on veterinary-sanitary ratings of meat, liver and kidneys of rabbits were realized. It was exposed stimulate influence of preparation to antioxidant status and increasing concen tration of trace elements (iron, iodine, selenium, cobalt, manganese, copper), that contains in preparation, in blood, liver, kidneys and muscles of rabbits (in the result of single intramuscular injection of 'Hexamin' in 200 mg/kg body mass dose). The preparation do not have teratogenic action by rats and negative influence on quality muscles, liver, kidneys of rabbits (but during 30 – 60 days in site of injection it was kept staining of tissues and was in need of peeling) and have weak annoyance influence on skin and tunica mucosa of laboratory animals.
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