Genetic Characterization of an Ancestral Strain of the Avian-Origin H3N2 Canine Influenza Virus Currently Circulating in East Asia
2016
Kim, J.K., Korea University, Sejong, Republic of Korea | Nam, J.H., Korea University, Sejong, Republic of Korea | Lyoo, K.S., Chonbuk National University, Iksan, Republic of Korea | Moon, H., Green Cross Veterinary Products, Yongin, Republic of Korea | Na, W., Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea | Song, E.J., Korea University, Sejong, Republic of Korea | Yeom, M., Korea University, Sejong, Republic of Korea | Shim, S.M., Korea University, Sejong, Republic of Korea | Jeong, D.G., Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea | An, D.J., Animal and Plant Quarantine Agency, Gimcheon, Republic of Korea | Kang, B.K., Green Cross Veterinary Products, Yongin, Republic of Korea | Song, D., Korea University, Sejong, Republic of Korea
H3N2 canine influenza virus emerged in South Korea in 2007 and subsequently spread to China and Thailand, causing epidemic or endemic respiratory diseases in dogs. Through intermammalian species transmission, the virus has also infected cats. However, no direct evidence of significant genetic evolution has been reported since its first emergence. Here, we describe in depth the genetic and molecular characteristics of the ancestral strain (i.e., the first virus isolate from South Korea) of the H3N2 canine influenza virus currently circulating in East Asia.
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