Genetic variations in open reading frame 2 gene of porcine circovirus type 2 isolated in Korea during 2016-2017
2018
Kim, K., Kangwon National University, Chuncheon, Republic of Korea | Choi, J.Y., Kangwon National University, Chuncheon, Republic of Korea | Lyoo, K.S., Chonbuk National University, Iksan, Republic of Korea | Hahn, T.W., Kangwon National University, Chuncheon, Republic of Korea
The capsid protein of porcine circovirus type 2 (PCV2) encoded by open reading frame 2 (ORF2) is important for neutralizing activity against PCV2 infection. This study investigated the heterogeneity of the ORF2 gene of PCV2 isolated in Korea during 2016-2017. The results revealed that PCV2d is currently the predominant genotype. Moreover, comparison of ORF2 from 17 PCV2 isolates revealed 88.3-100% homology at the nucleotide (deduced amino acid 86.3-100%) level. Interestingly, 61.5% (8/13) of the PCV2d isolates had glycine at position 210. These data provide a useful information for PCV2 epidemiology in Korea.
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