Anti-tyrosinase activity of orange peel extract and cosmetic formulation
2017
Thitilertdecha, N. | Boonmak J. | Kittigowittana, K. | Wuttisin, N. | Thaipitak, V.
The aims of this study were to determine anti-tyrosinase activity of ethanolic extract of orange peel, then develop the whitening cream from the extract and finally evaluate the satisfaction by users. The results showed that ethanol crude extracted had anti-tyrosinase activity with the IC50 of 255.10 µg/ml, which was less effective than kojic acid (23 times). Whitening cream containing orange peel extract 2% w/w was then formulated and tested for the satisfaction among 20 volunteers for 1 month compared with cream base. The results revealed that volunteers satisfy the properties of orange peel cream, i.e., texture, spread ability, absorption, and moisturization at high level, while odor properties was moderate satisfaction level. The average point of overall preference was high. After using orange peel cream for 1 month, the whitening improvement of volunteers’ skin color had been observed by skin color bar. Skin melanin content was measured before application of creams and then 1 month after using by Mexameter®. It was found that orange peel cream could reduce melanin pigment 17.33%. In addition, none of the volunteers developed irritation during the test period. It can be concluded that California Navel orange peel extract can be applied in cosmetic industry to increase the value of orange peel waste.
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