In vitro antigenotoksična aktivnost etanolskih ekstrakata korena biljke Salvia verticillata l. dobijenih različitim metodama ekstrakcije | In vitro antigenotoxic activity of ethanolic extracts of the Salvia verticillata L. root obtained by different extraction methods
2020
Srećković, Nikola | Mihailović, Vladimir | Katanić Stanković, Jelena | Matić, Sanja | Stanić, Snežana
In order to evaluate the DNA protective potential of ethanolic extracts of theroot of S. verticillata, prepared by different extraction methods, from damageinduced by the hydroxyl and peroxyl radicals two in vitro tests were used. For theextraction of the roots with ethanol as a solvent, three different methods wereapplied: ethnopharmacological, maceration and ultrasonic extraction. The extractsshowed an effective concentration-dependent reduction of DNA damage, withincreasing concentration of the extracts the protective effect decreases. Dependingon the extraction process of the plant material, slight differences in DNA protectivepotential of extracts were noticed.
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