Progress towards a non-surgical alternative to the mules operation for the control of blowfly strike [sheep]. [Conference paper]
1993
Chapman, R.E. (Commonwealth Scientific and Industrial Research Organisation, Blacktown (Australia). Div. of Animal Production)
A method is being investigated as a non-surgical alternative to the surgical Mules operation for the control of blowfly strike on the breech of sheep. It is based on the complexing and precipitation of the polyanionic glycosaminoglycans in skin with a cationic compound. When an appropriate compound is either injected intradermally or allied topically to the skin on the breech of sheep, a hard eschar forms within a few days. This eschar subsequently sloughs in four to eight weeks after intradermal injection and in three to four weeks after topical application. During the healing process leading to the sloughing of the eschar, a linear scar forms and the existing bare area on the breech is enlarged in a manner similar to that following the surgical Mules operation. The efficacy of various cationic quaternary ammonium compounds, amine oxides, imidazolines and imine compounds in removing skin from sheep is described, and results are presented of field trials with two quaternary ammonium compounds.
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