Antibody responses to avian encephalomyelitis virus vaccines when administered by different routes [chickens; layers]
1992
Shafren, D.R. | Tannock, G.A. (Newcastle Univ., Callaghan (Australia). Faculty of Medicine) | Grove, P.J. (Baiada Poultry, Pendle Hill (Australia))
Antibody responses to a commercial avian encephalomyelitis virus (AEV) vaccine administered by different routes were measured by an enzyme-linked immunosorbent assay (ELISA). Responses to single doses of vaccine administered by the ocular route to 10 percent of a flock were comparable with those obtained when all birds received a single dose in the drinking water. However, ocular vaccination of 5 percent of the flock resulted in significantly lower responses than those obtained when 10 percent were vaccinated. Maternal antibody was shown by the ELISA to persist in chickens from vaccinated flocks for up to 21 days after hatching. Day-old chickens with serum absorbance of less than 0.3 at 492 nm, as determined by the ELISA, were shown to be susceptible to intracerebral challenge with the neurotropic Van Roekel strain of AEV.
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