Abstract: Information on obesity is presented for health professionals and researchers. Three major aspects are addressed: procedures for measuring obesity in humans; incidence of obesity throughout the life cycle; and prevention and treatment of obesity. Muscle development and cardiovascular changes in the obese are discussed and intergenerational continuities and changes in obesity are examined. The accumulation of environmental contaminants (xenobiotics) in adipose tissue and their mobilization during weight reduction are described. The relevance of fat cell size and number with respect to infant, childhood, adolescent, and adult obesity is considered, along with the relationship of obesity to longevity and disease. Other topics explored include genetic and environmental factors influencing obesity, risk/benefit approaches to therapy, and new advances in dietary and surgical treatments for weight control and reduction. (nm)
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