Absorption of nutrients in lactase deficiency
1979
Debongnie, J.C. | Newcomer, A.D. | McGill, D.B. | Phillips, S.F.
Whether malabsorption of lactose, secondary to lactase deficiency, influenced absorption of other nutrients in milk (specifically protein, fat and minerals) was determined. An infusin-aspiration technique allowed quantification of flow through the terminal ileum after a test meal of milk. Four healthy volunteers and four with symptoms of milk intolerance ingested 250 ML of either whole or hydrolyzed milk containing a nonabsorbable marker (PEG 4000). The ileal flow increased in all subjects after the test meal. More fluid and nutrient was recovered in the lactase-deficient subjects after whole milk than in deficient subjects fed hydrolyzed milk or the control group. Two deficient subjects showed marked malabsorption of lactose; two did not. Protein, calcium, magnesium and phosphorus were recovered from the ileum in lactase deficients after whole milk. Apart from decreased absorption of lactose, the malabsorption of other nutrients has minimal consequences in adults.
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