Effect of a sunflower oil-supplemented diet on protein kinase activities of rat liver plasma membranes
1992
Gavrilova, N.J. | Setchenska, M.S. | Nikolova-Karakashian, M. | Petkova, D.J.
The effect of a sunflower oil-enriched diet on plasma membrane-bound protein kinase C, protein kinase A, casein and tyrosine kinase activities was studied. The diet induced an increase in the content of linoleic acid and a decrease in the content of palmitic acid. The anisotropy parameter (rs) of the fluorescence probe DPH and SDPH decreased strongly in the experimental group. Protein kinase C was stimulated more than two times. Tyrosine kinase, protein kinase A and casein kinase activities were increased by 65, 57 and 40%, respectively. We suggest that a more fluid lipid environment favours higher plasma membrane-bound protein kinase activities.
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