A novel construction of quino-fused tropone skeleton: first synthesis of 12H-benzo[4,5]cyclohepta[1,2-b]quinolin-12-one derivatives
2014
Gao, Wentao | Xing, Xueda | Li, Yang | Lan, Shuai
In the present investigation, the incorporation of both quinoline moiety and tropone ring in a molecule frame work in fused form leading to a series of structurally novel and biologically intriguing quinoline/tropone hybrids 12H-benzo[4,5]cyclohepta[1,2-b]quinolin-12-one derivatives has been first achieved through a simple, and economical two-step procedure, involving the one-pot synthesis of (E)-2-(arylvinyl)quinoline-3-carboxylic acids followed by intramolecular Friedel–Crafts acylation reaction using polyphosphoric acid (PPA).
Mostrar más [+] Menos [-]Palabras clave de AGROVOC
Información bibliográfica
Este registro bibliográfico ha sido proporcionado por National Agricultural Library