Genetic and environmental factors in determining obesity
1978
Winick, Myron
Extract: Two types of obesity have now been well documented: 1) Hypertrophic obesity in which the individual has a normal number of large fat cells; 2) Hyperplastic obesity in which the individual has an increased number of normal sized fat cells. It is now known that the adult number of fat cells is established during childhood. What this number will be is determined by the rate of fat cell division and the length of time fat cells continue to divide. Genetic obesity may be due to an increased rate of fat cell division which continues for an abnormally long period of time. The environment, mainly the early state of nutrition, can alter the rate of cell division in both genetically obese and normal individuals.
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