Effect of soybean phytate content on calcium bioavailability in mature and immature rats
1993
Mason, A.C. | Weaver, C.M. | Kimmel, S. | Brown, R.K.
The effect of phytate content on calcium bioavailability from soy flour and isolated soy protein was studied in infant and adult rats. Soybeans were grown hydroponically in nutrient culture containing various levels of phosphorus to produce a range in phytate content and simultaneously labeled with 45Ca. Absorption of 45Ca from test meals prepared from the labeled soy flour or from formula prepared from isolated soy protein was calculated by comparing the accumulation of radionuclide by femurs and tailbones after the labeled test meal consumption to the accumulation of radioactivity by the target bones after intraperitoneal injection of label where the intestinal barrier is bypassed. Although dephytinizing resulted in the soy flour with the most available calcium, calcium absorption from the various flours was high and differences were generally small. Varying the concentration of endogenous phytate in soybeans had little effect on calcium absorption. Absorption of 45Ca from isolated soy protein was very high in infant rate compared to that in mature rats.
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