A novel pyrazolo[1,5-a]pyridine fluorophore and its application to detect pH in cells
2018
Zhang, Ping | Lv, Huaying | Duan, Guiyun | Dong, Jian | Ge, Yanqing
A new fluorescent probe based on pyrazolo[1,5-a]pyridine was synthesized and used to monitor the pH in cells. This probe exhibited a fast response to acidic pH (less than 10 s), a high quantum yield (φ = 0.64), and high selectivity and sensitivity. The response mechanism of the fluorescent probes relies on the ICT change.
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