Synthesis and antibacterial activity of chalcones bearing prenyl or geranyl groups from Angelica keiskei
2011
Sugamoto, Kazuhiro | Matsusita, Yoh-ichi | Matsui, Kana | Kurogi, Chiaki | Matsui, Takanao
Chalcones bearing prenyl or geranyl groups from Angelica keiskei, such as 4-hydroxyderricin (1a), xanthoangelol (1e), xanthoangelol F (1f), xanthoangelol H (2), deoxyxanthoangelol H (3), and deoxydihydroxanthoangelol H (4) and their derivatives were synthesized. From the evaluation of antibacterial activity of the synthesized chalcones, 1a, isobavachalcone (1b), 1e, 1f, bavachalcone (5a), and broussochalcone B (5b) were found to inhibit Gram-positive bacteria.
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