Independence of the effects of cholesterol and degree of saturation of the fat in the diet on serum cholesterol in man
1976
Anderson, Joseph T. | Grande, Francisco | Keys, Ancel
Extract: The effect on the fasting serum lipid levels of adding daily 291 mg of cholesterol to diets containing 3 mg of cholesterol and equal fat content, but different fatty acid composition, was tested on 12 young men. Addition of cholesterol produced a mean elevation of serum cholesterol of 9 mg/dl in the presence of the saturated diet, and of 8 mg/dl in the presence of the polyunsaturated diet. Both cholesterol elevations were significant but not significantly different from each other. Substitution of the saturated diet for the polyunsaturated diet caused a significant elevation of serum cholesterol which was the same when the substitution was made in the presence or in the absence of added dietary cholesterol.
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