AI-2 to the rescue against antibiotic-induced intestinal dysbiosis?
2015
Sun, Zhongke | Grimm, Verena | Riedel, Christian U.
The downside of antibiotic treatment of infectious diseases is a disturbed intestinal microbiota leading to reduced resistance against pathogen colonization. Work by Thompson et al. now suggests that antibiotic-induced intestinal dysbiosis can partially be counterbalanced by artificially increasing the levels of autoinducer-2 (AI-2), a well-known bacterial communication molecule.
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