Effect of Ascorbic Acid Isomeric Forms on Antibacterial Activity of Its Chitosan Salts
2018
Gegel’, N. O. | Zudina, I. V. | Malinkina, O. N. | Shipovskaya, A. B.
Optical rotatory dispersion studies revealed water solutions of chitosan in L- and D-ascorbic acid to exhibit right rotation with anomalous dispersion and left rotation with normal dispersion, respectively. Microbiological investigation and transmission electron microscopy revealed the chitosan salt with D-ascorbic acid to cause deeper destructive changes than pure chitosan, which resulted in higher antibacterial activity against Staphylococcus aureus 209P and Escherichia coli 113-13.
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