Mn–Fe layered double hydroxide nanosheets: a new photothermal nanocarrier for O₂-evolving phototherapy

Ruan, Yudi; Jia, Xiaodai; Wang, Chao; Zhen, Wenyao; Jiang, Xiue

Mn–Fe layered double hydroxide nanosheets: a new photothermal nanocarrier for O₂-evolving phototherapy

2018

Ruan, Yudi | Jia, Xiaodai | Wang, Chao | Zhen, Wenyao | Jiang, Xiue

Iron–manganese layered double hydroxide nanosheets were developed as an effective photothermal nanocarrier for loading a photosensitizer. The catalase-like activity enables the nanosheets to decompose H₂O₂ into O₂, overcoming tumor hypoxia and enhancing O₂-dependent photodynamic therapy (PDT). The combination of PDT and photothermal therapy (PTT) can almost completely eliminate tumor tissues.

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