One-pot chemoenzymatic syntheses of enantiomerically-enriched O-acetyl cyanohydrins from aldehydes in ionic liquid
2008
Shen, Zhi-Liang | Zhou, Wei-Juan | Liu, Ya-Ting | Ji, Shun-Jun | Loh, Teck-Peng
A practical and efficient method for the synthesis of optically active O-acetyl cyanohydrins via one-pot lipase-catalyzed kinetic resolution of the in situ generated racemic cyanohydrins or O-acetyl cyanohydrins using an ionic liquid as both reaction media and promoter has been described.
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