The biocatalytic conversion of 8-hydroxymanzamine A to manzamine A
2003
Kasanah, N. | Rao, K.V. | Yousaf, M. | Wedge, D.E. | Hamann, M.T.
The selective dehydroxylation of 8-hydroxymanzamine A (...1) to form manzamine A (...2) can be completed by fermentation with Fusarium solani or Streptomyces seokies. This unique biocatalytic conversion is important due to the fact that manzamine A has more desirable biological activity when assayed in a murine model against malaria.
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