Effects of Myricetin‐Containing Ethanol Solution on High‐Fat Diet Induced Obese Rats
2017
Chao, Hsueh‐Chin | Tsai, Pei‐Feng | Lee, Sheng‐Chi | Lin, Yeong‐Shenn | Wu, Ming‐Chang
Myricetin is a natural flavonol widely occurring in wines. Many beneficial effects of myricetin in alcoholic beverages have been reported before, but never including anti‐obesity. In the present study, we fed obese male Sprague–Dawley rats with ethanol solutions containing various concentrations of myricetin and found that myricetin may maintain the food intake while reduce the weight‐gain, feed efficiency, level of blood lipids, adipocyte size, and weight and size of the perirenal and epididymal adipose tissues (P < 0.01). Our experiment data also show that the anti‐obesity effect may be associated with the upregulation of adropin and β‐endorphin levels. Based on the above‐described findings, we propose the potential for myricetin‐containing alcoholic beverages to be developed into anti‐obesity health food.
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