Dietary patterns and risk of ulcerative colitis: a case–control study
2018
Rashvand, S. | Behrooz, M. | Samsamikor, M. | Jacobson, K. | Hekmatdoost, A.
BACKGROUND: Recent evidence indicates a role for dietary factors in the pathogenesis of ulcerative colitis (UC). The aim of the present study was to investigate the relationship between dietary patterns and UC risk. METHODS: Sixty‐two newly diagnosed cases of UC and 124 healthy age and sex‐matched controls were studied. Data on diet was measured using a validated country‐specific food frequency questionnaire. Factor analysis was used to define major dietary patterns based on 28 food groups and nutrient content. RESULTS: After adjustment for confounding factors, subjects who were in the highest tertile of the healthy dietary pattern had a 79% lower risk of UC (odds ratio = 0.21, 95% confidence interval = 0.07–0.59, P = 0.003), whereas the consumption of an unhealthy dietary pattern was associated with a significantly increased risk of UC (odds ratio = 3.39, 95% 95% confidence interval = 1.16–9.90, P = 0.027). CONCLUSIONS: The findings of the present study suggest that dietary patterns are associated with UC risk.
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