First Description of an Escherichia coli Strain Producing NDM-1 Carbapenemase in Spain
2011
Solé, Mar | Pitart, Cristina | Roca, Ignasi | Fàbrega, Anna | Salvador, Pilar | Muñoz Mata, Laura | Oliveira, Inês | Gascón, Joaquim | Marco, Francesc | Vila, Jordi
A carbapenem-resistant Escherichia coli strain (DVR22) was recovered from a stool specimen from a patient with traveler's diarrhea who had traveled to India. Molecular screening led to the first identification of NDM-1 in Spain. The blaNDM-1 gene was located in a conjugative plasmid of ca. 300 kb that also contained the blaCTX-M-15, blaTEM-1, ΔblaDHA-1, and armA genes. In addition, blaNDM-1 was preceded by an ISAba125 insertion element only found in Acinetobacter spp.
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