A non-intrusive evaluation method for tumor-targeting characteristics of nanomedicines based on in vivo near-infrared fluorescence imaging
2019
Liu, Hao | Marquez, Rebecca T. | Wu, Xiaoqing | Li, Ke | Vadlamani, Shweta | Li, Song | Wang, Ya | Xu, Liang | Wu, Daocheng
We developed a novel evaluation method for tumor-targeting characteristics of nanomedicines, average tumor-targeting index (average TTI) and “area under the tumor-targeting index-time curve” (AUTC) were established as the indicators for tumor targeting of nanomedicines based on NIR fluorescence imaging, which helps real-time monitoring of targeting ability and tumor changes in vivo without culling animals.
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