Main components of gene network controlling development of dorsal appendages of egg chorion in Drosophila melanogaster
2012
Omelina, E. S. | Baricheva, E. M.
The development of dorsal appendages of the chorion (specialized structures in the D. melanogaster egg which look like elastic tubes and ensure the breathing of the developing embryo) is an attractive model for the study of genetic mechanisms of the development of organs and tissues, whose generation is based on transformation of the epithelial tissue in the tubular structures. In the present review, we present information on genes and proteins that control the development of dorsal appendages of the chorion. We demonstrated that three signal pathways (EGFR, DPP, and NOTCH), which are combined together in a single gene network through a number of components, play a major role in the development of dorsal appendages of the chorion.
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