Proportion of paternal marker gametes identified in progeny
1992
Gaillard, C. | Smith, C.
SUMMARY: Marker assisted selection (MAS) depends on the proportion of offspring which are informative. Formulas are presented which calculate the average proportion of progeny in which the different paternal gametes are 1) known to be transmitted and 2) can be identified in the progeny, when the linkage phase of the sire is known. The expressions were derived first for one marker and then for two markers per quantitative trait locus (QTL). Only a limited proportion of sires (or linkage groups within a sire) will be doubly (or triply) heterozygous for the marker(s) and the QTL. This greatly restricts the practical value of MAS. For doubly or triply heterozygous sires, the proportions of informative progeny for MAS are generally moderate to high. With more information (two markers vs. one marker, mates typed for the marker bs. mates not typed), the proportions become high. In the future with many polymorphic marker loci, the proportion of parents which are informative will be increased, so MAS will become more efficient.
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