Phytochemical study and evaluation of the antioxidant activity of Fredolia aretioides root extracts of Algeria | Composition chimique et activité antioxydante d’extraits organiques des racines de Fredolia aretioides de la région de Béchar en Algérie
2014
Bentabet, N. | Boucherit-Otmani, Z. | Boucherit, K.
The current research concerns essentially the study of antioxidant molecules of natural origin. This study falls into this context and consists in making at first a phytochemical screening of some extracts of the roots of Fredolia aretioides, an endemic plant of the region of Béchar (Algeria). Secondly, we estimated the antioxidant activity of these extracts. The phytochemical study allowed to highlight the existence of alkaloids, tanins and saponines in the roots. Coumarins were also present but in small quantities. In addition, the methanol extract of the roots contained a high content of total phenols, estimated at 971.05 mg/100 g GAE (gallic acid equivalent). The antioxidant activity of different extracts was evaluated by two methods, the reduction of iron and free radical scavenging of DPPH (2,2-diphenyl-1-picrylhydrazyl). Reduction capacity of iron is remarkable in the aqueous extract and alkaloids. Scavenging capacity of DPPH free radical is very interesting with an IC₅₀= 0.54 mg/ml, the latter is greater than the capacity of DPPH radical-scavenging ascorbic acid whose IC₅₀= 0.08 mg/ml.
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