High-performance capillary electrophoretic method for the determination of blasticidin S in formulated products
1995
Lo, C.C. | Lee, Y. J. | Chang, C.J.
An HPCE method with a UV-vis detector was used to determine blasticidin S content in commercial products. The results indicated that this method was capable of analyzing the blasticidin S content in formulated products with an instrument detection limit of 0.05 microgram/mL, a method detection limit of 0.2 microgram/mL, and RSD values from 0.61 to 8.11%. The HPCE method was promising in distinguishing between blasticidin S compounds and possible imitation antibiotic fungicides. The small quantity of injection volume and one-day analysis of seven samples indicated the HPCE method is a labor-saving and material-reducing technique. Thus, the present official bioassay method could be replaced by the HPCE method.
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