A new dimeric stilbene from the lianas of Gnetum parvifolium
2017
Tian, Li-Wen | Lv, Jun-Jiang | Liu, Yao | Song, Lu-Yao | Hou, Lian-Bing | Zhong, Cheng | Xie, Yang
A new dimeric stilbene, gnetifolin P (1), was isolated from the lianas of Gnetum parvifolium , together with seven known compounds 2 – 8 . The structure of compound 1 was determined by extensive NMR and HRESIMS data analyses, and quantum chemical calculations. All the compounds were evaluated for their anti-inflammatory activity. Compounds 1 and 6 inhibited the expression of IL-1β on LPS induced THP-1 cells with the inhibition rate of 35.78 and 64.67%, respectively, at concentration of 25 μg/mL.
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