(+/-)-Heterocarpine, a hydroxymethylated isoquinoline alkaloid from Ceratocapnos heterocarpa
1998
Suau, R. | Posadas, N. | Silva, M.V. | Valpuesta, M.
Heterocarpine, a novel alkaloid from Ceratocapnos heterocarpa, has been characterised as (+)-1-hydroxymethyl-2-(3-hydroxy-4-methoxybenzyl)-7- hydroxy-6-methoxy-1,2,3,4-tetrahydroisoquinoline. The alkaloid was synthesized from the corresponding 3,4-dihydro isoquinoliniun salt. A key step in the process is the acid resin catalysed methanolysis of the 1-carbamoyl isoquinoline. The structural correlation of the hydroxymethylated alkaloids heterocarpine and malacitanine with their unsubstituted counterparts capnosine and caseamine, also present in the plant, might be of biosynthetic significance.
Mostrar más [+] Menos [-]Palabras clave de AGROVOC
Información bibliográfica
Este registro bibliográfico ha sido proporcionado por National Agricultural Library