Influence of the ingestion of glutamine or glutamic acid in hepatic steatosis, growth and nitrogen balance after extensive enterectomy in rats
2001
Iglesias, A.C. | Braulio, V.B. | Jordao, A.A. Jr | Ceneviva, R. | Zucoloto, S. | Marchini, J.S. | Vannucchi, H.
The objective of the present study was to determine whether the addition of glutamine or glutamic acid to an amino acid diet would interfere with growth, nitrogen balance and liver fat content following extensive enterectomy in rats. These animals were fed an isocaloric and isonitrogenous diet whose nitrogen source was a mixture of amino acids, without (Group I) or with glutamine (Group II). An additional group was not eterectomized and received a casein-based diet (Group III). Weight evolution and nitrogen balance were similar for Groups I and II. Albumin levels were lower (p<0.05) in Group I, in addiction to greatest amount of fat in the liver when compared to Group II and Group III. In conclusion, the animals that received diet containing glutamine had a lesser liver fat content than animals that received diet without glutamine. However, no effect on growth and nitrogen balance was observed between enterectomized groups.
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