Antimutagenic Activity of 8-Hydroxyisoflavones and 6-Hydroxydaidzein from Soybean Miso
2003
Chen, Yuqi | INABA, Miyuki | ABE, Naoki | HIROTA, Akira
The antimutagenic activity of four isoflavones isolated from soybean miso toward three kinds of mutagens, AF-2, MNNG, and Trp-P-1, was evaluated by the Ames test. 8-Hydroxyisoflavones had greater suppressive potency than that of daidzein, and 6-hydroxydaidzein had almost the same activity as daidzein. These results indicated the number of hydroxy and methoxy groups and the position of these functional groups were important for antimutagenic activity.
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