NIR-responsive carbon-based nanocarriers for switchable on/off drug release and synergistic cancer therapy
2018
NieThese authors contributed equally to this work., Rongrong | Liu, Hongji | Hu, Lin | Gu, Xinyu | Qian, Junchao | Wang, Hui
Herein, we present a light-switchable drug delivery system based on chitosan-gated carbon-based nanocarriers (CGC NCs) that exhibit a loading capacity for doxorubicin as high as ∼89.65 wt% and controlled on/off release with/without NIR irradiation. In vitro and in vivo results show that the CGC NCs manifest high efficacy for cancer therapy through a synergistic effect of combined chemo-photothermal treatment.
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